[Vaccination against Haemophilus influenzae type b in the Valencia Community: efficacy and failure of vaccinations].
Identifieur interne : 000687 ( Main/Exploration ); précédent : 000686; suivant : 000688[Vaccination against Haemophilus influenzae type b in the Valencia Community: efficacy and failure of vaccinations].
Auteurs : A. Morant Gimeno ; J. Díez Domingo ; A. Rosales Marza ; R. Moreno Mu Oz ; P. L Pez García ; A. Herrero Galiana ; C. Gimeno Cardona ; J. Brimes SolanesSource :
- Anales espanoles de pediatria [ 0302-4342 ] ; 1998.
Descripteurs français
- KwdFr :
- MESH :
- administration et posologie : Vaccins anti-Haemophilus.
- immunologie : Grippe humaine, Haemophilus influenzae type B.
- prévention et contrôle : Grippe humaine.
- épidémiologie : Espagne.
- Enfant d'âge préscolaire, Humains, Mâle, Nourrisson, Vaccination.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Haemophilus Vaccines.
- geographic , epidemiology : Spain.
- immunology : Haemophilus influenzae type b, Influenza, Human.
- prevention & control : Influenza, Human.
- Child, Preschool, Humans, Infant, Male, Vaccination.
Abstract
OBJECTIVE
To study Haemophilus influenzae type b (Hib) conjugate vaccine effectivity and vaccine failures in the Valencian Community of Spain where vaccine can be obtained, but is not scheduled as a routine immunization.
PATIENTS AND METHODS
A prospective surveillance system where pediatricians and microbiologists of all public hospitals of the Valencian Community reported cases of invasive Hib disease in children (under 15 years of age). Vaccination status (number of doses, dates and type of vaccine) in each case was obtained.
RESULTS
Of 23 cases reported from December 1, 1995 to November 30, 1996, two had received at least one dose of Hib vaccine. One was a true vaccine failure and the other an apparent vaccine failure. Estimating a vaccine coverage of 32.5% of the children less than 5 years old, the direct vaccine effectivity was 90.6% (IC 95%: 27.9-98.8%).
CONCLUSIONS
Hib conjugate vaccine is effective in the Valencian Community, however, there is still invasive disease due to the low vaccine coverage and some vaccine failures.
PubMed: 9629790
Affiliations:
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Le document en format XML
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Moreno Mu Oz</name></author><author><name sortKey="L Pez Garcia, P" sort="L Pez Garcia, P" uniqKey="L Pez Garcia P" first="P" last="L Pez García">P. L Pez García</name></author><author><name sortKey="Herrero Galiana, A" sort="Herrero Galiana, A" uniqKey="Herrero Galiana A" first="A" last="Herrero Galiana">A. Herrero Galiana</name></author><author><name sortKey="Gimeno Cardona, C" sort="Gimeno Cardona, C" uniqKey="Gimeno Cardona C" first="C" last="Gimeno Cardona">C. Gimeno Cardona</name></author><author><name sortKey="Brimes Solanes, J" sort="Brimes Solanes, J" uniqKey="Brimes Solanes J" first="J" last="Brimes Solanes">J. Brimes Solanes</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1998">1998</date><idno type="RBID">pubmed:9629790</idno><idno type="pmid">9629790</idno><idno type="wicri:Area/Main/Corpus">00691</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">00691</idno><idno type="wicri:Area/Main/Curation">000691</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000691</idno><idno type="wicri:Area/Main/Exploration">000691</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Vaccination against Haemophilus influenzae type b in the Valencia Community: efficacy and failure of vaccinations].</title><author><name sortKey="Morant Gimeno, A" sort="Morant Gimeno, A" uniqKey="Morant Gimeno A" first="A" last="Morant Gimeno">A. Morant Gimeno</name><affiliation><nlm:affiliation>Instituto de Salud Carlos III, Unitat d'Investigació Trinitat, Valencia.</nlm:affiliation><wicri:noCountry code="subField">Valencia</wicri:noCountry></affiliation></author><author><name sortKey="Diez Domingo, J" sort="Diez Domingo, J" uniqKey="Diez Domingo J" first="J" last="Díez Domingo">J. Díez Domingo</name></author><author><name sortKey="Rosales Marza, A" sort="Rosales Marza, A" uniqKey="Rosales Marza A" first="A" last="Rosales Marza">A. Rosales Marza</name></author><author><name sortKey="Moreno Mu Oz, R" sort="Moreno Mu Oz, R" uniqKey="Moreno Mu Oz R" first="R" last="Moreno Mu Oz">R. Moreno Mu Oz</name></author><author><name sortKey="L Pez Garcia, P" sort="L Pez Garcia, P" uniqKey="L Pez Garcia P" first="P" last="L Pez García">P. L Pez García</name></author><author><name sortKey="Herrero Galiana, A" sort="Herrero Galiana, A" uniqKey="Herrero Galiana A" first="A" last="Herrero Galiana">A. Herrero Galiana</name></author><author><name sortKey="Gimeno Cardona, C" sort="Gimeno Cardona, C" uniqKey="Gimeno Cardona C" first="C" last="Gimeno Cardona">C. Gimeno Cardona</name></author><author><name sortKey="Brimes Solanes, J" sort="Brimes Solanes, J" uniqKey="Brimes Solanes J" first="J" last="Brimes Solanes">J. Brimes Solanes</name></author></analytic><series><title level="j">Anales espanoles de pediatria</title><idno type="ISSN">0302-4342</idno><imprint><date when="1998" type="published">1998</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Child, Preschool (MeSH)</term><term>Haemophilus Vaccines (administration & dosage)</term><term>Haemophilus influenzae type b (immunology)</term><term>Humans (MeSH)</term><term>Infant (MeSH)</term><term>Influenza, Human (immunology)</term><term>Influenza, Human (prevention & control)</term><term>Male (MeSH)</term><term>Spain (epidemiology)</term><term>Vaccination (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Enfant d'âge préscolaire (MeSH)</term><term>Espagne (épidémiologie)</term><term>Grippe humaine (immunologie)</term><term>Grippe humaine (prévention et contrôle)</term><term>Haemophilus influenzae type B (immunologie)</term><term>Humains (MeSH)</term><term>Mâle (MeSH)</term><term>Nourrisson (MeSH)</term><term>Vaccination (MeSH)</term><term>Vaccins anti-Haemophilus (administration et posologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Haemophilus Vaccines</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins anti-Haemophilus</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term><term>Haemophilus influenzae type B</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Haemophilus influenzae type b</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child, Preschool</term><term>Humans</term><term>Infant</term><term>Male</term><term>Vaccination</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Enfant d'âge préscolaire</term><term>Humains</term><term>Mâle</term><term>Nourrisson</term><term>Vaccination</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To study Haemophilus influenzae type b (Hib) conjugate vaccine effectivity and vaccine failures in the Valencian Community of Spain where vaccine can be obtained, but is not scheduled as a routine immunization.</p></div><div type="abstract" xml:lang="en"><p><b>PATIENTS AND METHODS</b></p><p>A prospective surveillance system where pediatricians and microbiologists of all public hospitals of the Valencian Community reported cases of invasive Hib disease in children (under 15 years of age). Vaccination status (number of doses, dates and type of vaccine) in each case was obtained.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Of 23 cases reported from December 1, 1995 to November 30, 1996, two had received at least one dose of Hib vaccine. One was a true vaccine failure and the other an apparent vaccine failure. Estimating a vaccine coverage of 32.5% of the children less than 5 years old, the direct vaccine effectivity was 90.6% (IC 95%: 27.9-98.8%).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Hib conjugate vaccine is effective in the Valencian Community, however, there is still invasive disease due to the low vaccine coverage and some vaccine failures.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9629790</PMID><DateCompleted><Year>1998</Year><Month>06</Month><Day>30</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0302-4342</ISSN><JournalIssue CitedMedium="Print"><Volume>48</Volume><Issue>4</Issue><PubDate><Year>1998</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Anales espanoles de pediatria</Title><ISOAbbreviation>An. Esp. Pediatr.</ISOAbbreviation></Journal><ArticleTitle>[Vaccination against Haemophilus influenzae type b in the Valencia Community: efficacy and failure of vaccinations].</ArticleTitle><Pagination><MedlinePgn>352-4</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To study Haemophilus influenzae type b (Hib) conjugate vaccine effectivity and vaccine failures in the Valencian Community of Spain where vaccine can be obtained, but is not scheduled as a routine immunization.</AbstractText><AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">A prospective surveillance system where pediatricians and microbiologists of all public hospitals of the Valencian Community reported cases of invasive Hib disease in children (under 15 years of age). Vaccination status (number of doses, dates and type of vaccine) in each case was obtained.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Of 23 cases reported from December 1, 1995 to November 30, 1996, two had received at least one dose of Hib vaccine. One was a true vaccine failure and the other an apparent vaccine failure. Estimating a vaccine coverage of 32.5% of the children less than 5 years old, the direct vaccine effectivity was 90.6% (IC 95%: 27.9-98.8%).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Hib conjugate vaccine is effective in the Valencian Community, however, there is still invasive disease due to the low vaccine coverage and some vaccine failures.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Morant Gimeno</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Instituto de Salud Carlos III, Unitat d'Investigació Trinitat, Valencia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Díez Domingo</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Rosales Marza</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Moreno Muñoz</LastName><ForeName>R</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>López García</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Herrero Galiana</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Gimeno Cardona</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Brimes Solanes</LastName><ForeName>J</ForeName><Initials>J</Initials></Author></AuthorList><Language>spa</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><VernacularTitle>Vacunación frente a Haemophilus influenzae tipo b en la Comunidad Valenciana: Efectividad vacunal y fallos vacunales. Grupo de Estudio de Enfermedades Invasoras.</VernacularTitle></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>An Esp Pediatr</MedlineTA><NlmUniqueID>0420463</NlmUniqueID><ISSNLinking>0302-4342</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018073">Haemophilus Vaccines</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018073" MajorTopicYN="N">Haemophilus Vaccines</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019741" MajorTopicYN="N">Haemophilus influenzae type b</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014611" MajorTopicYN="Y">Vaccination</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1998</Year><Month>6</Month><Day>18</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1998</Year><Month>6</Month><Day>18</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1998</Year><Month>6</Month><Day>18</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">9629790</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Brimes Solanes, J" sort="Brimes Solanes, J" uniqKey="Brimes Solanes J" first="J" last="Brimes Solanes">J. Brimes Solanes</name><name sortKey="Diez Domingo, J" sort="Diez Domingo, J" uniqKey="Diez Domingo J" first="J" last="Díez Domingo">J. Díez Domingo</name><name sortKey="Gimeno Cardona, C" sort="Gimeno Cardona, C" uniqKey="Gimeno Cardona C" first="C" last="Gimeno Cardona">C. Gimeno Cardona</name><name sortKey="Herrero Galiana, A" sort="Herrero Galiana, A" uniqKey="Herrero Galiana A" first="A" last="Herrero Galiana">A. Herrero Galiana</name><name sortKey="L Pez Garcia, P" sort="L Pez Garcia, P" uniqKey="L Pez Garcia P" first="P" last="L Pez García">P. L Pez García</name><name sortKey="Morant Gimeno, A" sort="Morant Gimeno, A" uniqKey="Morant Gimeno A" first="A" last="Morant Gimeno">A. Morant Gimeno</name><name sortKey="Moreno Mu Oz, R" sort="Moreno Mu Oz, R" uniqKey="Moreno Mu Oz R" first="R" last="Moreno Mu Oz">R. Moreno Mu Oz</name><name sortKey="Rosales Marza, A" sort="Rosales Marza, A" uniqKey="Rosales Marza A" first="A" last="Rosales Marza">A. 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